Time-resolved structural dynamics as a drug design platform showcased on an oncogenic signal complex

• Unité de recherche: INNOSUISSE
• Numéro de projet: 138.988 IP-LS
• Titre du projet anglais: Time-resolved structural dynamics as a drug design platform showcased on an oncogenic signal complex

Mots-clé (Anglais)

Life sciences, Biotechnology and processing

Résumé des résultats (Abstract) (Anglais)

This project develops a general platform for time-resolved structural dynamics analysis in drug discovery. Integrating mixing-based and light-activated triggering methods with X-ray crystallography and cryo-EM enables direct insight into transient protein states relevant to diverse drug targets.