Time-resolved structural dynamics as a drug design platform showcased on an oncogenic signal complex

Research unit

INNOSUISSE

Project number

138.988 IP-LS

Project title

Time-resolved structural dynamics as a drug design platform showcased on an oncogenic signal complex

Texts for this project

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Key words	-	-	-
Abstract	-	-	-

Category	Text
Key words (English)	Life sciences, Biotechnology and processing
Abstract (English)	This project develops a general platform for time-resolved structural dynamics analysis in drug discovery. Integrating mixing-based and light-activated triggering methods with X-ray crystallography and cryo-EM enables direct insight into transient protein states relevant to diverse drug targets.