Organoid-guided discovery of Thymus-regenerative ligands for immune rejuvenation

• Unité de recherche: INNOSUISSE
• Numéro de projet: 133.714 IP-LS
• Titre du projet anglais: Organoid-guided discovery of Thymus-regenerative ligands for immune rejuvenation

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

TECregen and the University of Basel will develop standardized human iPSC-derived thymus organoids, including - for the first time - a DiGeorge syndrome model, to accelerate screening of TECregen's engineered thymopoietic ligands as candidates for therapies restoring thymic function and immunity.