Validation and Expansion of the HelixScreen 3D Ex Vivo Drug Screening Platform for Colorectal Cancer and Antibody-Drug Conjugate Screening

Research unit

INNOSUISSE

Project number

137.138 INNO-LS

Project title

Validation and Expansion of the HelixScreen 3D Ex Vivo Drug Screening Platform for Colorectal Cancer and Antibody-Drug Conjugate Screening

Texts for this project

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Key words	-	-	-
Abstract	-	-	-

Category	Text
Key words (English)	Life sciences, Human medicine
Abstract (English)	This research evaluates HelixScreen - a high?throughput and rapid drug testing platform with transcriptomic profiling on 3D tumor cultures, that guides ADC payload selection and reveals antibody penetration in solid tumors, surpassing genomic?only or patient-derived xenograft limits.