TOP-N53 and PLGA Based Dissolving Microneedles for Transdermal Restoration of Microcirculation in Systemic Sclerosis Patients.

Forschungsstelle

INNOSUISSE

Projektnummer

108.683 INT-LS

Projekttitel

TOP-N53 and PLGA Based Dissolving Microneedles for Transdermal Restoration of Microcirculation in Systemic Sclerosis Patients.

Projekttitel Englisch

TOP-N53 and PLGA Based Dissolving Microneedles for Transdermal Restoration of Microcirculation in Systemic Sclerosis Patients.

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Schlüsselwörter	-	-	-
Abstract	-	-	-

Kategorie	Text
Schlüsselwörter (Englisch)	Life sciences, Pharmaceuticals, Material sciences
Abstract (Englisch)	Systemic sclerosis (SSc) is a debilitating rare disease. By developing microneedles that contain slow-release PLGA microspheres loaded with TOP-N53, a drug that combines NO donor and PDE5 inhibitor, we aim to mitigate secondary Raynaud's Phenomenon (RP) and prevent digital ulcers in SSc patients.