Development of a First-in-Class RNA Therapy for ADTKD-UMOD

• Unité de recherche: INNOSUISSE
• Numéro de projet: 131.332 IP-LS
• Titre du projet anglais: Development of a First-in-Class RNA Therapy for ADTKD-UMOD

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

The project aims to develop a novel antisense oligonucleotide therapy for inherited kidney disease. Having established in vivo proof-of-concept in a challenging genotype, we will now optimize medicinal chemistry and explore strategies that broaden patient coverage improved pharmaceutical properties.