PyoBeta: Pyoverdine-?-lactam prodrugs as novel antimicrobials against antibiotic-resistant bacteria

Research unit

INNOSUISSE

Project number

132.720 IP-LS

Project title

PyoBeta: Pyoverdine-?-lactam prodrugs as novel antimicrobials against antibiotic-resistant bacteria

Texts for this project

	German	French	Italian	English
Key words	-	-	-
Abstract	-	-	-

Category	Text
Key words (English)	Life sciences, Biotechnology and processing
Abstract (English)	We are developing a new class of antimicrobials that exploit bacterial iron dependency to treat systemic infections caused by WHO priority pathogens. Engineered pyoverdine-based prodrugs activate only at infection sites, starving pathogens of iron.