Advancing AAV gene therapies with synthetic biology solutions

• Unité de recherche: INNOSUISSE
• Numéro de projet: 125.805 IP-LS
• Titre du projet anglais: Advancing AAV gene therapies with synthetic biology solutions

Mots-clé (Anglais)

Life sciences, Biotechnology and processing

Résumé des résultats (Abstract) (Anglais)

AAV vectors are key for gene therapy, but current production methods face scalability and cost challenges. We develop producer cell lines with orthogonal ligand-inducible gene switches to optimize AAV yields, quality, and potency, advancing gene therapy production and metabolic disease treatment.