First-in-Class PAM Targetting Adenosine 2A Receptor: Developmental Candidate Selection and Validation of Autoimmune Disease Indications

Research unit

INNOSUISSE

Project number

121.127 IP-LS

Project title

First-in-Class PAM Targeting Adenosine 2A Receptor: Developmental Candidate Selection and Validation of Autoimmune Disease Indications

Texts for this project

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Key words	-	-	-
Abstract	-	-	-

Category	Text
Key words (English)	Life sciences, Pharmaceuticals
Abstract (English)	Adenosine 2A receptor (A2AR) signaling dysregulation results in inflammatory diseases. This project focuses on reaching the developmental drug candidate stage for positive allosteric modulators (PAMs) for A2AR and selecting the most relevant inflammatory therapeutic area(s) for their application.