Magnetic Resonance at the Scale of a Cell

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Identifiant

Unité de recherche

SEFRI

Numéro de projet

24.00156

Titre du projet

Magnetic Resonance at the Scale of a Cell

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	Allemand	Français	Italien	Anglais
Résumé des résultats (Abstract)	-	-	-

Textes saisis

Catégorie	Texte
Résumé des résultats (Abstract) (Anglais)	The HyperCell project merges two groundbreaking technologies to validate a benchtop tool for cell metabolic analysis, promising to revolutionize cell research. It empowers researchers to explore individual cell metabolic profiles, unveiling hidden disease mechanisms, understanding organism development, and revealing treatment responses. This innovation fills a crucial gap in the field, as current methods struggle to provide reliable metabolic data at the micro to picolitre scale. HyperCell's standout feature is its non-invasive approach to deliver quantitative metabolic information at the single-cell level without disrupting cell metabolism. This unique capability positions ANNAIDA and NVISION as global leaders in NMR technology, offering an unmatched solution in the market. The initial application for this technology is embryo analysis, addressing infertility, a widespread issue affecting one in six couples globally. The project will focus on the optimization, integration and validation of NVISION's Quantum-Based Platform, which Enhances NMR spectrometers' sensitivity to metabolites via hyperpolarization, enabling real-time monitoring of intracellular metabolic activity, with ANNAIDA’s Embryospin Sensor Technology Tailored for microscale NMR.

Catégorie

Texte

Résumé des résultats (Abstract)
(Anglais)

The HyperCell project merges two groundbreaking technologies to validate a benchtop tool for cell metabolic analysis, promising to revolutionize cell research. It empowers researchers to explore individual cell metabolic profiles, unveiling hidden disease mechanisms, understanding organism development, and revealing treatment responses. This innovation fills a crucial gap in the field, as current methods struggle to provide reliable metabolic data at the micro to picolitre scale. HyperCell's standout feature is its non-invasive approach to deliver quantitative metabolic information at the single-cell level without disrupting cell metabolism. This unique capability positions ANNAIDA and NVISION as global leaders in NMR technology, offering an unmatched solution in the market. The initial application for this technology is embryo analysis, addressing infertility, a widespread issue affecting one in six couples globally. The project will focus on the optimization, integration and validation of NVISION's Quantum-Based Platform, which Enhances NMR spectrometers' sensitivity to metabolites via hyperpolarization, enabling real-time monitoring of intracellular metabolic activity, with ANNAIDA’s Embryospin Sensor Technology Tailored for microscale NMR.