Targeting Methylated ERG with an Intracellular Minibody for the Treatment of Prostate Cancer

• Unité de recherche: INNOSUISSE
• Numéro de projet: 115.456 IP-LS
• Titre du projet anglais: Targeting Methylated ERG with an Intracellular Minibody for the Treatment of Prostate Cancer

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

We developed an intracellular antibody to inhibit with high potency and selectivity a post-translationally modified transcription factor that drives prostate cancer progression. In this project, we will conduct preclinical studies to advance this therapeutic approach toward clinical development.