Development of small molecule MSI1/2 inhibitors to treat memory disorders

• Unité de recherche: INNOSUISSE
• Numéro de projet: 123.289 IP-LS
• Titre du projet anglais: Development of small molecule MSI1/2 inhibitors to treat memory disorders

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

Accelerated forgetting in diseases like Alzheimer?s lacks effective treatments. We identified Musashi1/2 (MSI) as key to memory loss and developed MSI inhibitors now entering lead optimization. We aim to further develop this series to improve efficacy, IP position and drug-like properties.