Development of small molecule MSI1/2 inhibitors to treat memory disorders

• Forschungsstelle: INNOSUISSE
• Projektnummer: 123.289 IP-LS
• Projekttitel Englisch: Development of small molecule MSI1/2 inhibitors to treat memory disorders

Schlüsselwörter (Englisch)

Life sciences, Pharmaceuticals

Abstract (Englisch)

Accelerated forgetting in diseases like Alzheimer?s lacks effective treatments. We identified Musashi1/2 (MSI) as key to memory loss and developed MSI inhibitors now entering lead optimization. We aim to further develop this series to improve efficacy, IP position and drug-like properties.