Small Molecule Inhibitors to an RNA modifying enzyme as a Slimming Pill

• Unité de recherche: INNOSUISSE
• Numéro de projet: 103.580 IP-LS
• Titre du projet anglais: Small Molecule Inhibitors to an RNA modifying enzyme as a Slimming Pill

Mots-clé (Anglais)

Life sciences, Human medicine

Résumé des résultats (Abstract) (Anglais)

The aim of this project is to conduct a small molecule screen for identifying inhibitors for an RNA modifying enzyme and test its use as a "slimming pill" in reducing obesity in mice. Knockout of this enzyme results in a lean phenotype in mice and protects animals from diet-induced obesity.