Abstract
(Englisch)
|
RealCare is a cutting-edge research initiative focused on developing and validating next-generation point-of-care (PoC) systems thatdetect essential biomarkers in human biofluids in real-time. These systems are designed to be compact, energy-efficient, and integratedwith extended reality interfaces, with a specific emphasis on cancer and cardiac diseases in demanding clinical settings. RealCare'sapproach includes advanced biomarker detection technologies, such as microfluidics and new generations of microneedles, label-freeelectrochemical biosensors using 2D materials, optical sensors utilizing CRISPR, biological amplifiers combined with fluorescentmicroscopy, and scalable SPR with energy-efficient electronic readouts, AI data processing, and wireless communication units.Additionally, RealCare will design portable, interoperable, and adaptable PoC systems that integrate the biomarker detection technologywith vital sign monitoring, including advanced data analytics and AI methods. The initiative also focuses on developing intuitive extendedreality interfaces, such as augmented and virtual reality, to visualize biomarker data in real-time and facilitate rapid medical decisionmakingin integrated in-care environments and workflows. Rigorous clinical validation studies will be conducted in relevant clinicalsettings, including the surgery room, ICU, and patient's home, to ensure accuracy, reliability, usability, and impact on patient outcomes.RealCare places special attention on including a diverse patient population in their studies to validate the effectiveness of the developedsystems. Data quality, interoperability, and medical data protection are key considerations in RealCare's strategy. Based on our uniquePoC technological platform and our strong, multidisciplinary consortium partnership, we propose promising lab-to-market paths withthe potential for significant societal impact.
|
