Covalent proximity scanning ? unleashing covalent PI3Kalfa inhibitors for cancer

Research unit

INNOSUISSE

Project number

108.486 IP-LS

Project title

Covalent proximity scanning ? unleashing covalent PI3Kalfa inhibitors for cancer

Texts for this project

	German	French	Italian	English
Key words	-	-	-
Abstract	-	-	-

Category	Text
Key words (English)	Life sciences, Human medicine
Abstract (English)	PI3K? is a high value target in cancer. Response duration and tolerability of approved PI3K? drugs is limited. With our proprietary CoPS platform for covalent inhibitor deployment, we will generate novel covalent PI3K? inhibitors with enhanced specificity and potency ready for clinical development.