Development of an MCT1/4 dual inhibitor as an anti-cancer drug

• Unité de recherche: INNOSUISSE
• Numéro de projet: 103.872 IP-LS
• Titre du projet anglais: Development of an MCT1/4 dual inhibitor as an anti-cancer drug

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

The lactate transporters MCT1 and MCT4 are validated cancer drug targets. No MCT4 inhibitor has entered clinical testing. We have developed a drug series with dual MCT1 and MCT4 inhibition. We aim to further develop this series to improve efficacy, IP position and drug-like properties.