The second generation of Wnt inhibitors: FZD5-selective inhibitors to treat cancer

• Unité de recherche: INNOSUISSE
• Numéro de projet: 105.987 IP-LS
• Titre du projet anglais: The second generation of Wnt inhibitors: FZD5-selective inhibitors to treat cancer

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

We have identified selective and unique FZD5 inhibitors that have the potential to become best-in-class. The purpose of this project is to support drug discovery to identify a lead compound with appropriate pharmacokinetics and in vivo efficacy in a TNBC rodent model.