Adenosine 2A receptor reactivation by positive allosteric modulators as a new therapeutic venue for unmet medical need in chronic inflammation

• Unité de recherche: INNOSUISSE
• Numéro de projet: 102.479 IP-LS
• Titre du projet anglais: Adenosine 2A receptor reactivation by positive allosteric modulators as a new therapeutic venue for unmet medical need in chronic inflammation

Mots-clé (Anglais)

Life sciences, Medtech

Résumé des résultats (Abstract) (Anglais)

Based on new insights, past SAR campaigns are being re-challenged and rationalized for further hit-to-lead chemical optimization and future drug candidate selection. The project strength lies in the drug allosteric mode of action, an innovative and safer approach to chronic inflammation treatments.