Peptidoglycan hydrolase-loaded extracellular vesicles for the targeted treatment of intracellular bacterial infections

• Unité de recherche: INNOSUISSE
• Numéro de projet: 59414.1 IP-LS
• Titre du projet anglais: Peptidoglycan hydrolase-loaded extracellular vesicles for the targeted treatment of intracellular bacterial infections

Description succincte (Allemand)

Peptidoglycan hydrolase-loaded extracellular vesicles for the targeted treatment of intracellular bacterial infections

Description succincte (Anglais)

Peptidoglycan hydrolase-loaded extracellular vesicles for the targeted treatment of intracellular bacterial infections

Résumé des résultats (Abstract) (Allemand)

Staphylococcus aureus can proliferate within host cells, thereby escaping antibiotic therapy. We will establish functionalized extracellular vesicles as a novel drug delivery system for target-specific, intracellular delivery of peptidoglycan hydrolases with proven efficacy against S. aureus.