Peptidoglycan hydrolase-loaded extracellular vesicles for the targeted treatment of intracellular bacterial infections

• Unité de recherche: INNOSUISSE
• Numéro de projet: 59414.1 IP-LS
• Titre du projet anglais: Peptidoglycan hydrolase-loaded extracellular vesicles for the targeted treatment of intracellular bacterial infections

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

Staphylococcus aureus can proliferate within host cells, thereby escaping antibiotic therapy. We will establish functionalized extracellular vesicles as a novel drug delivery system for target-specific, intracellular delivery of peptidoglycan hydrolases with proven efficacy against S. aureus.