Payload technology to improve radioimmunotherapies - A novel treatment option for cancer patients resistant to chemotherapy

• Unité de recherche: INNOSUISSE
• Numéro de projet: 120.375 IP-LS
• Titre du projet anglais: Payload technology to improve radioimmunotherapies - A novel treatment option for cancer patients resistant to chemotherapy

Mots-clé (Anglais)

Life sciences, Pharmaceuticals

Résumé des résultats (Abstract) (Anglais)

We develop a novel antibody-radionuclide conjugate (ARC), L1CAM-Tb-161, offering a new therapeutic window for patients with resistance to chemotherapy. Based on our non-toxic polymer-payload technology we conjugate common & novel isotopes to an antibody targeting the human cell adhesion molecule L1.