Development of expandable, gastroretentive fibrous dosage forms: Precision manufacture, in vitro characterization, and validation of gastric residence in pigs and dogs

• Forschungsstelle: INNOSUISSE
• Projektnummer: 54994.1 IP-LS
• Projekttitel Englisch: Development of expandable, gastroretentive fibrous dosage forms: Precision manufacture, in vitro characterization, and validation of gastric residence in pigs and dogs

Kurzbeschreibung (Deutsch)

Development of expandable, gastroretentive fibrous dosage forms: Precision manufacture, in vitro characterization, and validation of gastric residence in pigs and dogs

Kurzbeschreibung (Englisch)

Development of expandable, gastroretentive fibrous dosage forms: Precision manufacture, in vitro characterization, and validation of gastric residence in vivo in pigs and dogs

Abstract (Deutsch)

Herein we propose the investigation of a gastroretentive dosage form that enables improved control of the drug concentration in blood, and more efficacious and safer drug therapies. A potential social benefit of the project is a better quality of life.