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Research unit
INNOSUISSE
Project number
35449.1 IP-LS
Project title
Non-competitive pharmacologic chaperones developed through the Site-directed Enzyme Enhancement Therapy (SEE-Tx) technology for the treatment of rare genetic and neurodegenerative diseases

Texts for this project

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Short description
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Abstract
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Short description
(German)
Non-competitive pharmacologic chaperones developed through the Site-directed Enzyme Enhancement Therapy (SEE-Tx) technology for the treatment of rare genetic and neurodegenerative diseases
Short description
(English)
Non-competitive pharmacologic chaperones developed through the Site-directed Enzyme Enhancement Therapy (SEE-Tx) technology for the treatment of rare genetic and neurodegenerative diseases
Abstract
(German)
In cellulo investigation of the mechanisms of action of non-competitive pharmacological chaperones that can recover misfolded mutant proteins and reduce the toxic accumulation of substrates therefore filling high unmet medical needs in the treatment of rare genetic and neurodegenerative disorders.