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Unité de recherche
OSAV
Numéro de projet
1.21.13
Titre du projet
ICRAD CAE-RAPID Development of a rapid screening test for on-site serological di-agnostics of caprine arthritis-encephalitis using individual milk samples

Textes relatifs à ce projet

 AllemandFrançaisItalienAnglais
Mots-clé
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Description succincte
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Objectifs du projet
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Publications / Résultats
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Textes saisis


CatégorieTexte
Mots-clé
(Allemand)

Afrikanische Schweinepest, Persistenz, Resistenz, Immunantwort

Description succincte
(Anglais)

The objective of CAE-RAPID is to develop a rapid immunochromatographic diagnostic test (point-of-care test) for caprine arthritis encephalitis (CAE).

CAE-RAPID aims to improve individual diagnostics of CAE by providing an easily available and convenient tool for reliable exclusion and early detection of the disease. The rapid test for detection of antibodies to SRLV in a drop of milk, serum, or whole blood will be intended for use in two basic situations. First, for on-site quick screening of asymptomatic goats which are intended to be purchased or introduced into the herd. Second, for on-site quick screening of goats in which ?rst clinical signs have emerged. The test will be a screening diagnostic method so it will be expected to maximize diagnostic sensitivity and the negative predictive value, so that a goat that tests negative can be safely introduced into or retained in the herd. Positive results will need veri?cation in the laboratory.
Objectifs du projet
(Anglais)
- Isolation und characterization of SRLV field strains.
- Production and purification of whole-virus antigen and recombinant SRLV proteins such as Env and Gag.
- Integrate these antigens in a point-of-care, rapid immunochromatographic diagnostic test.
Publications / Résultats
(Allemand)
Documents annexés