EZH2 Inhibitors: a new treatment opportunity with disease modifying potential for people with hereditary blindness

• Unité de recherche: INNOSUISSE
• Numéro de projet: 44271.1 IP-LS
• Titre du projet anglais: EZH2 Inhibitors: a new treatment opportunity with disease modifying potential for people with hereditary blindness

Description succincte (Allemand)

EZH2 Inhibitors: a new treatment opportunity with disease modifying potential for people with hereditary blindness

Description succincte (Anglais)

EZH2 Inhibitors: a new treatment opportunity with disease modifying potential for people with hereditary blindness

Résumé des résultats (Abstract) (Allemand)

No generic treatments are available for inherited retinal dystrophies resulting in blindness. We found that the inhibition of an enzyme involved in epigenetic modifications markedly improved cell survival, so we aim to determine the best existing drug to delay blindness in human in the near future.