Development of NLRP3-ASC selective inhibitors

• Unité de recherche: INNOSUISSE
• Numéro de projet: 38802.1 IP-LS
• Titre du projet anglais: Development of NLRP3-ASC selective inhibitors

Description succincte (Allemand)

Development of NLRP3-ASC selective inhibitors

Description succincte (Anglais)

Development of NLRP3-ASC selective inhibitors

Résumé des résultats (Abstract) (Allemand)

Inhibition of the NLRP3 Inflammasome is a promising strategy to fight certain diseases with an (auto-)immune component, including gout, arthritis, Alzheimer's and Parkinson's. We will develop, optimize and validate one or several new NLRP3 inhibitors, starting from an existing set of lead molecules.