Developing a next-generation targeted anti-fibrotic therapy for heart failure in a porcine model

• Forschungsstelle: INNOSUISSE
• Projektnummer: 121.274 IP-LS
• Projekttitel Englisch: Developing a next-generation targeted anti-fibrotic therapy for heart failure in a porcine model

Schlüsselwörter (Englisch)

Life sciences, Pharmaceuticals

Abstract (Englisch)

The project aims to demonstrate translational proof of concept of a Wisper-targeting antisense therapy in a porcine model of myocardial infarction and to gain further understanding of how doses, pharmacodynamics, and pharmacokinetics translate for this first-in-class therapeutic target.