Targeting mTOR Kinase in Cancer and Neurological Disorders

• Unité de recherche: INNOSUISSE
• Numéro de projet: 37213.1 IP-LS
• Titre du projet anglais: Targeting mTOR Kinase in Cancer and Neurological Disorders

Description succincte (Allemand)

Targeting mTOR Kinase in Cancer and Neurological Disorders

Description succincte (Anglais)

Targeting mTOR Kinase in Cancer and Neurological Disorders

Résumé des résultats (Abstract) (Allemand)

Hyperactivation of mechanistic target of rapamycin (mTOR) induces epilepsy, CNS dysfunction and benign tumors. Treatment options are ineffective and poorly tolerated. A first-in-class, brain-penetrant, selective inhibitor of mTOR kinase with improved tolerability and efficacy will be identified.

Résumé des résultats (Abstract) (Anglais)