Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway

Research unit

INNOSUISSE

Project number

33285.1 IP-LS

Project title

Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway

Texts for this project

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Short description		-	-
Abstract		-	-	-

Category	Text
Short description (German)	Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway
Short description (English)	Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway
Abstract (German)	Inhibitors against components of the LPS biosynthesis pathway as drugs against Gram-negative bacteria are developed using protein epitope mapping technology (PEM) developed by Polyphor. Structural data and studies to understand off-targeting are conducted at UZH to obtain preclinical candidates.