Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway

Forschungsstelle

INNOSUISSE

Projektnummer

33285.1 IP-LS

Projekttitel

Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway

Projekttitel Englisch

Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung		-	-
Abstract		-	-	-

Kategorie	Text
Kurzbeschreibung (Deutsch)	Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway
Kurzbeschreibung (Englisch)	Development of a new Class of Antibiotics Inhibiting the LPS Transport Pathway
Abstract (Deutsch)	Inhibitors against components of the LPS biosynthesis pathway as drugs against Gram-negative bacteria are developed using protein epitope mapping technology (PEM) developed by Polyphor. Structural data and studies to understand off-targeting are conducted at UZH to obtain preclinical candidates.