Feasibility study: Development of a lead compound for specific mTORC1 inhibition

• Unité de recherche: INNOSUISSE
• Numéro de projet: 28452.1 IP-LS
• Titre du projet anglais: Feasibility study: Development of a lead compound for specific mTORC1 inhibition

Description succincte (Allemand)

Feasibility study: Development of a lead compound for specific mTORC1 inhibition

Description succincte (Anglais)

Feasibility study: Development of a lead compound for specific mTORC1 inhibition

Résumé des résultats (Abstract) (Allemand)

The mammalian target of rapamycin complex 1 (mTORC1) is deregulated in multiple diseases. We aim to generate a lead compound that specifically inhibits mTORC1 by targeting substrate recruitment. We expect such a compound to be superior to current drugs for treating tuberous sclerosis complex.

Résumé des résultats (Abstract) (Anglais)