A Novel Hybrid Magnetic Nanomaterial for Proteomics Applications # [NanoProteoZyme]

Forschungsstelle

INNOSUISSE

Projektnummer

25597.1 PFNM-NM

Projekttitel

A Novel Hybrid Magnetic Nanomaterial for Proteomics Applications # [NanoProteoZyme]

Projekttitel Englisch

A Novel Hybrid Magnetic Nanomaterial for Proteomics Applications # [NanoProteoZyme]

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung		-	-
Abstract		-	-

Kategorie	Text
Kurzbeschreibung (Deutsch)	A Novel Hybrid Magnetic Nanomaterial for Proteomics Applications # [NanoProteoZyme]
Kurzbeschreibung (Englisch)	A Novel Hybrid Magnetic Nanomaterial for Proteomics Applications # [NanoProteoZyme]
Abstract (Deutsch)	The NanoProteoZyme project aims to develop novel nanotechnology-based formulations of protease enzymes for use in bioanalytics. The newly produced nanobiocatalysts shall display an enhanced resistance to chaotropic conditions, which are typically needed for the use of proteases in bioanalysis. When equipped with a magnetic core, the nanoparticles shall be straightforwardly separated from the reaction medium thus avoiding contamination issues. The enzyme formulation strategy is also expected to fully suppress autolysis reactions resulting in more reliable and reproducible enzymatic digestion assays.
Abstract (Englisch)	The NanoProteoZyme project aims to develop novel nanotechnology-based formulations of protease enzymes for use in bioanalytics. The newly produced nanobiocatalysts shall display an enhanced resistance to chaotropic conditions, which are typically needed for the use of proteases in bioanalysis. When equipped with a magnetic core, the nanoparticles shall be straightforwardly separated from the reaction medium thus avoiding contamination issues. The enzyme formulation strategy is also expected to fully suppress autolysis reactions resulting in more reliable and reproducible enzymatic digestion assays.