Novel carbohydrate-based vaccine against Actinobacillus pleuropneumoniae in pigs

• Unité de recherche: INNOSUISSE
• Numéro de projet: 25291.2 PFLS-LS
• Titre du projet anglais: Novel carbohydrate-based vaccine against Actinobacillus pleuropneumoniae in pigs

Description succincte (Allemand)

Novel carbohydrate-based vaccine against Actinobacillus pleuropneumoniae in pigs

Description succincte (Anglais)

Novel carbohydrate-based vaccine against Actinobacillus pleuropneumoniae in pigs

Résumé des résultats (Abstract) (Allemand)

Actinobacillus pleuropneumoniae (APP) is a major cause of economic loss in pig production and a cross-protective vaccine for all APP serotypes is highly requested by industry. This project uses a technology to express specific sugar moieties of APP on the surface of vector bacteria. The result will be vaccine strains expressing the different lipopolysaccharides or capsular polysaccharides corresponding to the different APP serotypes and a Pan-APP-vaccine.

Résumé des résultats (Abstract) (Anglais)

Actinobacillus pleuropneumoniae (APP) is a major cause of economic loss in pig production and a cross-protective vaccine for all APP serotypes is highly requested by industry. This project uses a technology to express specific sugar moieties of APP on the surface of vector bacteria. The result will be vaccine strains expressing the different lipopolysaccharides or capsular polysaccharides corresponding to the different APP serotypes and a Pan-APP-vaccine.