3D human liver microtissue-based in vitro assay for perdicting metabolic stability of low clearance compounds in pharmaceutical drug development

Research unit

INNOSUISSE

Project number

25720.1 PFLS-LS

Project title

3D human liver microtissue-based in vitro assay for perdicting metabolic stability of low clearance compounds in pharmaceutical drug development

Texts for this project

	German	French	Italian	English
Short description		-	-
Abstract		-	-

Category	Text
Short description (German)	3D human liver microtissue-based in vitro assay for perdicting metabolic stability of low clearance compounds in pharmaceutical drug development
Short description (English)
Abstract (German)	The projects aims at developing an in vitro assay based on primary human 3D spherical microtissues and microfluidic technology for analyzing pharmacokinetics of new compounds. The focus lies on low clearance substances and their stability over time in relation to liver metabolism.
Abstract (English)