High-content screening-compatible in vitro model for Alzheimer's disease in 3DProSeedTM microtiter plate and innovations in the 3DProSeedTM manufacturing technology.

• Research unit: INNOSUISSE
• Project number: 25383.1 PFLS-LS

Short description (German)

High-content screening-compatible in vitro model for Alzheimer's disease in 3DProSeedTM microtiter plate and innovations in the 3DProSeedTM manufacturing technology.

Short description (English)

Abstract (German)

A new assay concept for Alzheimer#s disease will be investigated in one part of the proposed project. The assay concept will be based on the innovative 3DProSeed technology enabling the sequential seeding of iPSC-derived neurons and glia cells within the same pre-assembled hydrogel. The other part of the project will be devoted to the development of 3DProSeed hydrogel production methods in order to meet the high reproducibility requirements of the industry to adopt 3D cell culture products.

Abstract (English)