Establishment of a fully synthetic, mirror-image biological system - Texte

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Forschungsstelle

INNOSUISSE

Projektnummer

19069.1 PFLS-LS

Projekttitel

Establishment of a fully synthetic, mirror-image biological system

Projekttitel Englisch

Establishment of a fully synthetic, mirror-image biological system

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung		-	-
Abstract		-	-

Erfasste Texte

Kategorie	Text
Kurzbeschreibung (Deutsch)	Establishment of a fully synthetic, mirror-image biological system
Kurzbeschreibung (Englisch)	Establishment of a fully synthetic, mirror-image biological system
Abstract (Deutsch)	Our goal is to create a mirror-image synthetic biology, independent of nature. Starting from L-nucleotides and D-amino acids, we will use chemical synthesis to establish a functioning mirror-image biological system from artificial components. There are immediate practical outcomes: D-DARPins will not be substrates of natural proteases, permitting oral application, and they may fundamentally overcome immunogenicity even in fusion proteins as therapeutic principles.
Abstract (Englisch)	Our goal is to create a mirror-image synthetic biology, independent of nature. Starting from L-nucleotides and D-amino acids, we will use chemical synthesis to establish a functioning mirror-image biological system from artificial components. There are immediate practical outcomes: D-DARPins will not be substrates of natural proteases, permitting oral application, and they may fundamentally overcome immunogenicity even in fusion proteins as therapeutic principles.