Development of a technology platform for the high throughput screening of mammalian cell clones and 3D cell cultures

• Research unit: INNOSUISSE
• Project number: 18364.2 PFLS-LS

Short description (German)

Entwicklung einer Matrix-basierten Technologieplattform für die Hochdurchsatz-Analyse von 3D Zellkulturen

Short description (English)

Development of a technology platform for the high throughput screening of mammalian cell clones and 3D cell cultures

Abstract (German)

The screening of large cell libraries is an important process in pharmaceutical discovery and R&D, e.g. to define drug targets or develop effective medicines. The goal of this project is the implementation of a screening platform based on 3D cultivation of mammalian cells encapsulated in hydrogels. To this end new hydrogel compositions will be designed, tested and finally utilized in a cultivation system that enables high throughput analysis of mammalian cell clones.

Abstract (English)

The screening of large cell libraries is an important process in pharmaceutical discovery and R&D, e.g. to define drug targets or develop effective medicines. The goal of this project is the implementation of a screening platform based on 3D cultivation of mammalian cells encapsulated in hydrogels. To this end new hydrogel compositions will be designed, tested and finally utilized in a cultivation system that enables high throughput analysis of mammalian cell clones.