New antileishmanial and antitrypanosomal drugs

• Unité de recherche: INNOSUISSE
• Numéro de projet: 19208.1 PFLS-LS
• Titre du projet anglais: New antileishmanial and antitrypanosomal drugs

Description succincte (Allemand)

Neue Wirkstoffe zur Behandlung der Leishmaniose und Chagas-Krankheit

Description succincte (Anglais)

New antileishmanial and antitrypanosomal drugs

Résumé des résultats (Abstract) (Allemand)

The aim is to develop a natural product derived LEAD compound with unrivalled potency against a parasitic disease into a clinical drug candidate, through preclinical development. This includes the establishment of a detailed structure-activity relationship (SAR), medicinal chemistry and organic synthesis, ADME-Tox optimization, formulation, and in vivo studies.

Résumé des résultats (Abstract) (Anglais)

The aim is to develop a natural product derived LEAD compound with unrivalled potency against a parasitic disease into a clinical drug candidate, through preclinical development. This includes the establishment of a detailed structure-activity relationship (SAR), medicinal chemistry and organic synthesis, ADME-Tox optimization, formulation, and in vivo studies.