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Research unit
INNOSUISSE
Project number
19208.1 PFLS-LS
Project title
New antileishmanial and antitrypanosomal drugs

Texts for this project

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Short description
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Abstract
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Inserted texts


CategoryText
Short description
(German)
Neue Wirkstoffe zur Behandlung der Leishmaniose und Chagas-Krankheit
Short description
(English)
New antileishmanial and antitrypanosomal drugs
Abstract
(German)
The aim is to develop a natural product derived LEAD compound with unrivalled potency against a parasitic disease into a clinical drug candidate, through preclinical development. This includes the establishment of a detailed structure-activity relationship (SAR), medicinal chemistry and organic synthesis, ADME-Tox optimization, formulation, and in vivo studies.
Abstract
(English)
The aim is to develop a natural product derived LEAD compound with unrivalled potency against a parasitic disease into a clinical drug candidate, through preclinical development. This includes the establishment of a detailed structure-activity relationship (SAR), medicinal chemistry and organic synthesis, ADME-Tox optimization, formulation, and in vivo studies.