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Research unit
INNOSUISSE
Project number
18929.1 PFLS-LS
Project title
DUAL CYTOKINE-ANTIBODY FUSIONS: next-generation antibody products for a selective modulation of the activity of the immune system at the site of disease

Texts for this project
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Short description
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Abstract
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CategoryText
Short description
(German)
DUAL CYTOKINE-ANTIBODY FUSIONS: next-generation antibody products for a selective modulation of the activity of the immune system at the site of disease
Short description
(English)
DUAL CYTOKINE-ANTIBODY FUSIONS: next-generation antibody products for a selective modulation of the activity of the immune system at the site of disease
Abstract
(German)
The use of recombinant antibodies as delivery vehicles promises to greatly enhance the therapeutic index of pro-inflammatory and anti-inflammatory cytokines. However, current generation immunocytokines do not elicit cures in vivo whereas combination immunocytokine therapies can. This project aims to develop 'second generation' immunocytokines to capitalize on this observation by combining synergistic cytokine pairs into a single therapeutic molecule
Abstract
(English)