Identification of IL-18 driven autoinflammatory conditions to develop specifc therapeutic interventions. - Texts

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Research unit

INNOSUISSE

Project number

18772.1 PFLS-LS

Project title

Identification of IL-18 driven autoinflammatory conditions to develop specifc therapeutic interventions.

Texts for this project

	German	French	Italian	English
Short description		-	-
Abstract		-	-

Inserted texts

Category	Text
Short description (German)	Identification of IL-18 driven autoinflammatory conditions to develop specifc therapeutic interventions.
Short description (English)	Identification of IL-18 driven autoinflammatory conditions to develop specifc therapeutic interventions.
Abstract (German)
Abstract (English)	Autoinflammatory diseases (AIDs) arise from the abnormal activation of the innate immune system and are characterized by recurrent febrile episodes, systemic inflammation triggered by unoticed pro-inflammatory signals. IL-1, IL-18 and Type I and II IFN are the major cytokines driving the clinical manifestations. The aim of this project is the identification of IL-18 driven AID for the implementation of specific treatments.