Development and validation of a sensitive, specific and robust high-throughput tool for monitoring, surveillance and certification of urogenital schistosomiasis elimination, based on real time PCR (RT PCR)

• Research unit: INNOSUISSE
• Project number: 18553.2 PFLS-LS

Short description (German)

Development and validation of a sensitive, specific and robust high-throughput tool for monitoring, surveillance and certification of urogenital schistosomiasis elimination, based on real time PCR (RT PCR)

Short description (English)

Development and validation of a sensitive, specific and robust high-throughput tool for monitoring, surveillance and certification of urogenital schistosomiasis elimination, based on real time PCR (RT PCR)

Abstract (German)

Abstract (English)

Highly sensitive diagnostic assays are mandatory for large-scale screening of humans and intermediate-host snails in control programmes moving towards schistosomiasis elimination. Swiss TPH and Biolytix AG will develop and validate a highly sensitive and specific, robust, high-throughput real-time (RT)-PCR system for monitoring progress towards urogenital schistosomiasis elimination in Africa, for surveillance after elimination has been achieved, and to certify urogenital schistosomiasis elimination in formerly endemic countries.