A novel, localized approach to immune checkpoint modulation for the therapy of cancer

Forschungsstelle

INNOSUISSE

Projektnummer

18269.2 PFLS-LS

Projekttitel

A novel, localized approach to immune checkpoint modulation for the therapy of cancer

Projekttitel Englisch

A novel, localized approach to immune checkpoint modulation for the therapy of cancer

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung		-	-
Abstract		-	-

Kategorie	Text
Kurzbeschreibung (Deutsch)	A novel, localized approach to immune checkpoint modulation for the therapy of cancer
Kurzbeschreibung (Englisch)	A novel, localized approach to immune checkpoint modulation for the therapy of cancer
Abstract (Deutsch)	The pathophysiology of chronic inflammation and epithelial cancer are casuatively linked. Interleukin (IL)-23 and IL-23 receptor (IL23R) expressing cells are heavily implicated in the development of various malignancies. In this project the potential of a bispecific antibody fragment specifically depleting IL23R expressing cells shall be evaluated to reactivate the host anti-cancer immune response.
Abstract (Englisch)	The pathophysiology of chronic inflammation and epithelial cancer are casuatively linked. Interleukin (IL)-23 and IL-23 receptor (IL23R) expressing cells are heavily implicated in the development of various malignancies. In this project the potential of a bispecific antibody fragment specifically depleting IL23R expressing cells shall be evaluated to reactivate the host anti-cancer immune response.