pH kinetics and antimicrobial efficacy of a calcium-based alkaline coating

• Unité de recherche: INNOSUISSE
• Numéro de projet: 19117.1 PFSATW-NM
• Titre du projet anglais: pH kinetics and antimicrobial efficacy of a calcium-based alkaline coating

Description succincte (Allemand)

T-2016-018: pH kinetics and antimicrobial efficacy of a calcium-based alkaline coating

Description succincte (Anglais)

pH kinetics and antimicrobial efficacy of a calcium-based alkaline coating

Résumé des résultats (Abstract) (Allemand)

Implant-associated infections cause dramatic implication for patients and the health care system and antimicrobial coatings are desired. We propose to assess a degradable calcium-based alkaline coating. Our aim is to develop a coating thick enough to generate alkaline conditions and inhibit bacterial growth. We will measure the pH-kinetics and its related antimicrobial effect. Our goal is to understand the structure-function relation and ensure antimicrobial efficacy in-vivo.

Résumé des résultats (Abstract) (Anglais)

Implant-associated infections cause dramatic implication for patients and the health care system and antimicrobial coatings are desired. We propose to assess a degradable calcium-based alkaline coating. Our aim is to develop a coating thick enough to generate alkaline conditions and inhibit bacterial growth. We will measure the pH-kinetics and its related antimicrobial effect. Our goal is to understand the structure-function relation and ensure antimicrobial efficacy in-vivo.