Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

• Unité de recherche: INNOSUISSE
• Numéro de projet: 19086.1 PFLS-LS
• Titre du projet anglais: Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Description succincte (Allemand)

Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Description succincte (Anglais)

Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Résumé des résultats (Abstract) (Allemand)

There is no efficient topical pharmacotherapy for delayed wound healing in corticosteroid treated patients. A topical agent encouraging re-epithelialization would address this unmet need. There is evidence that CS induce delayed wound healing. Recent studies have shown that spironolactone limits epidermal and corneal atrophy and accelerates wound healing; however its low aqueous solubility makes its topical use very difficult. ApidSOL formulation would overcome this problem.

Résumé des résultats (Abstract) (Anglais)