Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

• Research unit: INNOSUISSE
• Project number: 19086.1 PFLS-LS

Short description (German)

Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Short description (English)

Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Abstract (German)

There is no efficient topical pharmacotherapy for delayed wound healing in corticosteroid treated patients. A topical agent encouraging re-epithelialization would address this unmet need. There is evidence that CS induce delayed wound healing. Recent studies have shown that spironolactone limits epidermal and corneal atrophy and accelerates wound healing; however its low aqueous solubility makes its topical use very difficult. ApidSOL formulation would overcome this problem.

Abstract (English)