Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

• Forschungsstelle: INNOSUISSE
• Projektnummer: 19086.1 PFLS-LS
• Projekttitel Englisch: Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Kurzbeschreibung (Deutsch)

Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Kurzbeschreibung (Englisch)

Spironolactone-ApidSOL formulation for delayed healing of minor wounds in glucocorticoid treated patients

Abstract (Deutsch)

There is no efficient topical pharmacotherapy for delayed wound healing in corticosteroid treated patients. A topical agent encouraging re-epithelialization would address this unmet need. There is evidence that CS induce delayed wound healing. Recent studies have shown that spironolactone limits epidermal and corneal atrophy and accelerates wound healing; however its low aqueous solubility makes its topical use very difficult. ApidSOL formulation would overcome this problem.

Abstract (Englisch)