Lung-on-Chip for Pulmonary Fibrosis Compound Testing

• Unité de recherche: INNOSUISSE
• Numéro de projet: 18171.1 PFLS-LS
• Titre du projet anglais: Lung-on-Chip for Pulmonary Fibrosis Compound Testing

Description succincte (Allemand)

Lung-on-Chip for Pulmonary Fibrosis Compound Testing

Description succincte (Anglais)

Lung-on-Chip for Pulmonary Fibrosis Compound Testing

Résumé des résultats (Abstract) (Allemand)

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease with poor prognosis. Clinical evidence suggests that the mechanical strain induced by the respiration plays a key role in the progression of the disease. In contrast to current in-vivo and in-vitro models that poorly mimic key processes that take place in IPF, an advanced in-vitro model of the lung will be developed to test anti-fibrotic compounds.

Résumé des résultats (Abstract) (Anglais)