A Conformationally Unstable DNA-Based Biosensor for the fast Detection of Bacteria

• Unité de recherche: INNOSUISSE
• Numéro de projet: 17847.1 PFNM-NM
• Titre du projet anglais: A Conformationally Unstable DNA-Based Biosensor for the fast Detection of Bacteria

Description succincte (Allemand)

A Conformationally Unstable DNA-Based Biosensor for the fast Detection of Bacteria

Description succincte (Anglais)

A Conformationally Unstable DNA-Based Biosensor for the fast Detection of Bacteria

Résumé des résultats (Abstract) (Allemand)

We propose the development of a smart system for the recognition of the presence of pathogenic bacteria.|Our sensing element is composed of DNA, and acts by hybridization with bacterial ribosomal RNA and|subsequent release of a chemical moiety. The system is designed to be highly versatile and will be adapted|to the release of a colored substrate for sensing purposes or the release of a reactive substrate with antimicrobial properties for therapeutic purposes.

Résumé des résultats (Abstract) (Anglais)

We propose the development of a smart system for the recognition of the presence of pathogenic bacteria.|Our sensing element is composed of DNA, and acts by hybridization with bacterial ribosomal RNA and|subsequent release of a chemical moiety. The system is designed to be highly versatile and will be adapted|to the release of a colored substrate for sensing purposes or the release of a reactive substrate with antimicrobial properties for therapeutic purposes.