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Research unit
INNOSUISSE
Project number
17847.1 PFNM-NM
Project title
A Conformationally Unstable DNA-Based Biosensor for the fast Detection of Bacteria

Texts for this project

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Short description
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Abstract
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CategoryText
Short description
(German)
A Conformationally Unstable DNA-Based Biosensor for the fast Detection of Bacteria
Short description
(English)
A Conformationally Unstable DNA-Based Biosensor for the fast Detection of Bacteria
Abstract
(German)
We propose the development of a smart system for the recognition of the presence of pathogenic bacteria.|Our sensing element is composed of DNA, and acts by hybridization with bacterial ribosomal RNA and|subsequent release of a chemical moiety. The system is designed to be highly versatile and will be adapted|to the release of a colored substrate for sensing purposes or the release of a reactive substrate with antimicrobial properties for therapeutic purposes.
Abstract
(English)
We propose the development of a smart system for the recognition of the presence of pathogenic bacteria.|Our sensing element is composed of DNA, and acts by hybridization with bacterial ribosomal RNA and|subsequent release of a chemical moiety. The system is designed to be highly versatile and will be adapted|to the release of a colored substrate for sensing purposes or the release of a reactive substrate with antimicrobial properties for therapeutic purposes.